Dickkopf Proteins and Their Role in Cancer: A Family of Wnt Antagonists with a Dual Role
The Wnt signaling pathway regulates crucial aspects such as cell fate determination, cell polarity and organogenesis during embryonic development.Wnt Wooden Toy pathway deregulation is a hallmark of several cancers such as lung, gastric and liver cancer, and has been reported to be altered in others.Despite the general agreement reached by the scie